Autosomal Dominant Polycystic Kidney Disease: A Risk Factor for Berry Aneurysm
Autosomal dominant polycystic kidney disease is a genetical disorder caused by changes occurred in PKD1 and PKD2 genes and
is characterized mainly by the growth of multiple kidney cysts. It is progressive disorder with symptoms of high blood pressure,
pain in the back and the sides, and also headache. Patients having ADPKD are having a high risk of formation of intracranial
aneurysms. Presenting a case of ADPKD associated with subarachnoid hemorrhage with berry aneurysm and discussed about
the diagnostic approach with imaging modalities in this patient and the treatment.
Information Clearinghouse; 2015.
2. Harris T, Sandford R, EAF Members, Roundtable Participants. European
ADPKD Multidisciplinary position statement on autosomal dominant
polycystic kidney disease care: European ADPKD Forum and multispecialist
roundtable participants. Nephrol Dial Transplant 2018;33:563-73.
3. Chalouhi N, Hoh BL, Hasan D. Review of cerebral aneurysm formation,
growth, and rupture. Stroke 2013;44:3613-22.
4. Wang JW, Li CH, Tian YY, Li XY, Liu JF, Li H, et al. Safety and efficacy of
endovascular treatment of ruptured tiny cerebral aneurysms compared with
ruptured larger aneurysms. Interv Neuroradiol 2020;26:283-90.
5. Nornes H, Magnaes B. Intracranial pressure in patients with ruptured
saccular aneurysm. J Neurosurg 1972;36:537-4.