Validity of Pneumonia Severity Score in Predicting Mortality of Pediatric Patients in a Tertiary Care Hospital
Background: Pneumonia is estimated to kill 410,000 children in India every year. In India, recent estimates in under-fives suggest that 13% of deaths and 24% of the National Burden of Disease is due to pneumonia. Very few studies have evaluated the predictors of mortality in children with pneumonia in developing countries. Hence, this study was planned to study predictors of mortality in children aged 1–59 months based on pneumonia severity score (PSS) in hospitalized patients with severe pneumonia.
Objective: The objective of this study is to assess the factors (clinical and investigational) contributing to the mortality in patients based on PSS in hospitalized patients diagnosed with severe pneumonia.
Materials and Methods: The present observational longitudinal study was carried out in a tertiary care PICU in a Govt. NSCB Medical College, Jabalpur for of 1 years (Ian 2019–December 2019). Children diagnosed as severe pneumonia of either sex between age group 1–59 months admitted in a hospital were enrolled in the study. Demographic data, clinical details, and laboratory parameters of the enrolled cases were recorded in a predesigned pretested pro forma. PSS was calculated and correlated with the outcome of the patients enrolled and followed up till discharge or death.
Results: Mortality was observed in 11 cases, and of them, 4 (36.4%) were males and 7 (63.6%) patients were females. This study showed that among clinical parameters pulse rate and SpO2 were significantly raised (63.6%) and saturation was significantly <90 (72.7%) in children who succumbed to death (P < 0.05). This study observed a statistically highly significant association of PSS with the outcome of children (P < 0.01).
Proc Natl Acad Sci USA 2000;97:13286-93.
2. Management of the Child with a Serious Infection or Severe Malnutrition.
Guidelines for Care at the First Referral Level in Developing Countries.
Geneva: World Health Organization; 2000. Available from: http://www.
whqlibdoc.who.int/hq/2000/who_fch_cah_00.1.pdf. [Last accessed on
2015 Jul 01].
3. Sehgal V, Sethi GR, Sachdev HP, Satyanarayana L. Predictors of mortality
in subjects hospitalized with acute lower respiratory tract infections. Indian
4. Agrawal PB, Shendumikar N, Shastri NJ. Host factors and pneumonia in
hospitalized children. J Indian Med Assoc 1995;93:271-2.
5. Roy P, Sen PK, Das KB, Chakraborty AK. Acute respiratory infections
in children admitted in a hospital of Calcutta. Indian J Public Health
6. Tiewsoh K, Lodha R, Pandey RM, Broor S, Kalaivani M, Kabra SK. Factors
determining the outcome of children hospitalized with severe pneumonia.
BMC Pediatr 2009;9:15.
7. Djelantik IG, Gessner BD, Sutanto A, Steinhoff M, Linehan M, Moulton LH,
et al. Case fatality proportions and predictive factors for mortality among
children hospitalized with severe pneumonia in a rural developing country
setting. J Trop Pediatr 2003;49:327-32.
8. Banajeh SM, Al-Sunbali NN, Al-Sanohani SH. Clinical characteristics and
outcome of children aged under 5 years hospitalized with severe pneumonia
in Yemen. Ann Trop Paediatr 1997;17:321-6.
9. Mortensen EM, Garcia S, Leykum L, Nakashima B, Restrepo MI,
Anzueto A. Association of hypoglycemia with mortality for subjects
hospitalized with pneumonia. Am J Med Sci 2010;339:239-43.
10. Suwanjutha S, Ruandkanchanasetr S, Chantarojanasini T, Ttotrakitya S.
Risk factors associated with morbidity and mortality of pneumonia in
Thai children under 5 years. Southeast Asian J Trop Med Public Health