Clinico-Radiological and Pathological Profile of Lung Cancer Patients: An Experience from Tuberculosis and Chest Department of Indira Gandhi Institute of Medical Sciences, Patna: A Tertiary Health Care Centre of Bihar

  • Manish Shankar Associate Professor, Department of Tuberculosis and Chest
  • Kalyan Kumar Saha Senior Resident, Department of General Medicine
  • Praveen Kumar Associate Professor, Department of General Medicine
  • Saket Sharma Assistant Professor, Department of Pneumnology
  • Samir Kumar Senior Resident, Department of Tuberculosis and Chest
Keywords: Clinico-radiological profile, Lung cancer, Patna, Tuberculosis and chest

Abstract

Introduction: Today, lung cancer is the leading cause of cancer-related morbidity and mortality worldwide. Lung cancer especially shows varied epidemiological, clinico-radiological, and pathological profile. Majority of patients are at advanced stages before reaching to hospital. Lung cancers are growing at fast pace due to smoking habits, especially in Bihar. There are very sparse data of lung cancer patients especially in this part of the world.
Aim: This study aims to evaluate the clinico-radiological, demographic, and pathological profile of lung cancer patients reaching to Tuberculosis (TB) and Chest Department of Indira Gandhi Institute of Medical Sciences (IGIMS), Patna, Bihar and to assess the yield of various diagnostic processes used for the diagnosis.
Materials and Methods: This is a retrospective observational study done between September 2016 and February 2018 at TB and Chest Department of IGIMS, Patna, Bihar which is a tertiary health-care institute. Around 216 of proven lung cancer patients were enrolled for the study. Their history, clinical details, radiological, pathological, and demographic profiles recorded in the departmental records were analyzed in details using SPSS software.
Results: A total of 216 patients were included in our study of which 154 (71.29%) were male and 62 (28.7%) were female. Most patients were in the age bracket 66–75 years (33.88%). Most of the patients belonged to rural background (65.27%). About 71.29% of patients were smokers or former smokers. Adenocarcinoma was the most common histological subtypes documented, i.e., 89 patients (41.20%).
Computed tomography scan and ultrasonography-guided percutaneous biopsy combined was the most common modality of successfully diagnosing lung cancer, in about 25.92%. Majority of patients reached in advanced stage 63.88% among non-small cell lung cancer before arriving to health care facility (in Stage IVA). Mass was the most common radiological diagnosis in about 42.59%.
Conclusion: Adenocarcinoma is the leading type of lung cancer found in this study especially in this part of the world. Moreover, there is growing trend of lung cancer among females. Smoking is still the leading cause. Majority of patients reach at an advanced stage before diagnosis. Hence, aggressive approach is needed for earlier diagnosis of lung cancer for timely management.

Author Biographies

Manish Shankar, Associate Professor, Department of Tuberculosis and Chest

Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India

Kalyan Kumar Saha, Senior Resident, Department of General Medicine

Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India

Praveen Kumar, Associate Professor, Department of General Medicine

 Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India

Saket Sharma, Assistant Professor, Department of Pneumnology

Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India

Samir Kumar, Senior Resident, Department of Tuberculosis and Chest

Indira Gandhi Institute of Medical Sciences, Patna, Bihar, India

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Published
2021-10-02