Polycystic Ovary Syndrome Confers Additional Hormonal Level Abnormalities: A Study in Tertiary Care Hospital on Bengali Obese Women

  • Md. Sadique Mallick Nilratan Sircar (NRS) Medical College and Hospital 138 A.J.C. Bose Road, Kolkata, West Bengal, India
  • Serina Khatun Medical College, Kolkata, West Bengal, India
Keywords: Insulin resistance, Obese, Polycystic ovary syndrome

Abstract

Introduction: Polycystic ovary syndrome (PCOS) is one of the most frequently encountered endocrine disorders in women of reproductive
age. Adiposity plays a crucial role in PCOS and influences the clinical and endocrine features in many women with this condition.
Purpose: This aim of the study was to compare hormonal abnormalities in women with obese Bengali PCOS cases attending
in a government hospital with body mass index (BMI) matched women without PCOS in West Bengal.
Methods: A total of 75 obese PCOS patients (ethnic Bengali) were recruited and 75 BMI matched control were taken, and
PCOS was diagnosis according to the Rotterdam criteria (2003). Serum follicle stimulating hormone (FSH), luteinizing hormone
(LH), FSH/LH ratio, plasma glucose, insulin glucose/insulin ratio, and serum total testosterone were measured.
Results: Study serum LH, LH/FSH ratio, serum fasting insulin, and serum total testosterone levels were higher, and serum
insulin/glucose ratio is lower than their obese BMI-matched controls.
Conclusion: Polycystic ovary syndrome confers additional hormonal level abnormalities in Bengali obese PCOS women in West Bengal.

Author Biographies

Md. Sadique Mallick, Nilratan Sircar (NRS) Medical College and Hospital 138 A.J.C. Bose Road, Kolkata, West Bengal, India

Department of Physiology, 

Serina Khatun, Medical College, Kolkata, West Bengal, India

Department of Physiology, 

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Published
2018-06-14