Effects of Oral Submucous Fibrosis on Auditory Tube Function: A Case–control Study

  • Ambrish Kumar Bhagwan Mahavir Medica Superspecialty Hospital, Ranchi, Jharkhand, India
Keywords: Impedance audiometry, Middle ear pressure, Oral submucous fibrosis

Abstract

Background: Oral submucous fibrosis (OSMF) is a precancerous condition, recognized as collagen disease with resemblance
to localized scleroderma. The study is to analyze the middle ear pressure of OSMF patients of various grades of disease.
Materials and Methods: A total of 40 OSMF patients (80 ears) and 40 healthy controls (80 ears) were analyzed for middle ear
pressure by the use of impedance audiometry.
Results: The impedance audiometry test shows statistically significant difference in middle ear pressure of OSMF patients
and control.
Conclusion: The study suggests that the middle ear pressure may be affected by disease and its progression.

Author Biography

Ambrish Kumar, Bhagwan Mahavir Medica Superspecialty Hospital, Ranchi, Jharkhand, India

Department of ENT, 

References

1. Pindborg JJ, Sirsat SM. Oral submucous fibrosis. Oral Surg Oral Med Oral
Path 1966;22:764-79.
2. Tilakaratne WM, Klinikowski MF, Saku T, Peters TJ, Warnakulasuriya S.
Oral submucous fibrosis: Review on aetiology and pathogenesis. Oral
Oncology 2006;42:561-8.
3. Rajendran R. Oral submucous fibrosis. J Oral Maxillofac Pathol 2003;7:1-4.
4. Rooban T, Saraswati TR,Al Zainab FH, Devi U, Eligabeth J, Rangnathan KA light microscopic study of fibrosis involving muscle in oral submucous
fibrosis. Ind J Dent Res 2005;16:131-4.
5. El Labban NG, Caniff JP. Ultra structural finding of muscle degeneration in
oral submocus fibrosis. J Oral Pathol 1985;14:709-17.
6. Gupta SC, Khanna S, Singh M, Singh PA. Histological changes to palatal
and paratubal muscles in oral submucous fibrosis. J Laryngol Otol
2000;114:947-50.
7. Shah M, Katarkar A, Shah P, Alam N, Modh D. Tympanometric study
of eustachian tube function in oral submucous fibrosis. Indian J Otol
2011;17:80-2.
8. Kerr AR, Warnakulasuriya S, Mighell AJ, Dietrich T, Nasser M, Rimal J.
A systematic review of medical interventions for oral submucous fibrosis
and future research opportunities. Oral Dis 2011;17 Suppl 1:42-57.
9. Auluck A, Rosin MP, Zhang L, Sumanth KN. Oral submucous fibrosis, a
clinically benign but potentially malignant disease: Report of 3 cases and
review of the literature. JCDA 2008;74:735-40.
10. Smitha BR, Donoghue M. Clinical and histopathological evaluation of
collagen fibre orientation in patients with oral submucous fibrosis. J Oral
Maxillofac Pathol 2011;15:154-60.
11. Borle RM, Borle SR. Management of oral submucous fibrosis:
A conservative approach. J Oral Maxillofac Surg 1991;49:SR788-91.
12. Caniff JP, Harvey W, Harris M. Oral submucous fibrosis- its pathogenesis
and management. Br Dent J 1986;160:429-34.
13. McGurk M, Craig GT. Oral submucous fibrosis: Two cases of malignant
transformation in Asian immigrants to the United Kingdom. Br J Oral
Maxillofac Surg 1984;22:56-64.
14. Misra SP, Misra V, Dwivedi M, Gupta SC. Oesophageal subepithelial
fibrosis: An extension of oral submucosal fibrosis. Postgrad Med J
1998;74:733-6.
15. Ranganathan K, Devi MU, Joshua E, Kirankumar K, Saraswathi TR. Oral
submucous fibrosis: A case-control study in Chennai, South India. J Oral
Pathol Med 2004;33:274-7.
16. Gupta SC, Singh M, Khanna S, Jain S. Oral submocous fibrosis with its
possible effect on eustachian tube functions: A tympanometric study. Ind J
Otolaryngol Head Neck Surg 2004;56:183-5.
17. Pundir S, Saxena S, Aggrawal P. Oral submucous fibrosis a disease with
malignant potential - Report of two cases. J Clin Exp Dent 2010;2:e215-8.
18. Rajlalitha P, Vali S. Molecular pathogenesis of oral submucous fibrosis - a
collegen metabolic disorder. J Oral Pathol Med 2005;34:321-8.
19. Pindborg JJ, Sirsat SM. Oral submucous fibrosis oral. Surg Oral Med Oral
Pathol 1966;22:764-79.
20. Utsunomiya H, Tilakaratne WM, Oshiro K, Maruyama S, Suzuki M, IdaYonemochi H. Extracellular matrix remodeling in oral submucous fibrosis:
Its stage-specific modes revealed by immunohistochemistry and in situ
hybridization. J Oral Pathol Med 2005;34:498-507.
21. More CB, Das S, Patel H, Adalja C, Kamatchi V, Venkatesh R. Proposed
clinical classification for oral submucous fibrosis. Oral Oncol 2012;48:200-2.
22. Lai DR, Chen HR, Lin LM, Huang YL, Tsai CC. Clinical evaluation
of different treatment methods for oral submucous fibrosis. A 10 year
experience with 150 cases. J Oral Pathol Med 1995;24:402-6.
23. Binnie WA, Cawson RA. A new ultra structural finding in oral submucous
fibrosis. Br J Dermatol 1972;86:286-90.
24. Oliver AJ, Radden BG. Oral submucous fibrosis. Case report and review of
literature. Aust Dent J 1992;37:31-4
Published
2018-06-13